Paper - Review

DOI: 10.1007/s00441-010-1034-0

Abstract

The complement system
→ consist of a tightly regulated network of proteins
← that play an important role ← in 1⃣ host defense 2⃣ inflammation

Complement activation
→ results → in 1⃣ opsonization of pathogens 2⃣ their removal by phagocytosis
← e.g. 1⃣ cell lysis

1⃣ Inappropriate complement activation 2⃣ complement deficiencies
→ are the underlying cause ← of (the pathophysiology of many diseases)
← e.g. 1⃣ systemic lupus erythematosus 2⃣ asthma

∴ An overview of (the complement system)
← in 1⃣ an effort → to understand the beneficial 2⃣ harmful roles → it plays during (inflammatory responses)

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